Basic Information

IDDRAMP00396
SequenceNLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFDC
Length49
NameCt-AMP1 (CtAMP1, C. ternatea-antimicrobial peptide 1; Plant defensin)
SourceClitoria ternatea
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacterium: Bacillus subtilis (IC50=15 µg/mL).##Medium A: Botrytis cinerea (IC50=20 µg/ml), Cladosporium sphaerospermum (IC50=6 µg/ml), Fusarium culmorum (IC50=10 µg/ml), Leptosphaeria maculans (IC50=6 µg/ml), Penicillium digitatum (IC50=20 µg/ml), Trichoderma viride (IC50>100 µg/ml), Septoria tritiei (IC50=2 µg/ml), Verticilium albo-atrum (IC50=2 µg/ml). NOTE: Medium B = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 µg/ml), Cladosporium sphaerospermum (IC50=100 µg/ml), Fusarium culmorum (IC50=50 µg/ml), Leptosphaeria maculans (IC50=20 µg/ml), Penicillium digitatum (IC50=80 µg/ml), Trichoderma viride (IC50>100 µg/ml), Septoria tritiei (IC50=80 µg/ml), Verticilium albo-atrum (IC50>100 µg/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7628617

Physicochemical Properties

Residues49
SequenceNLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFDC
Molecular Weight5614.221
Grand Average of Hydropathy-0.849
Isoelectric Point8.21
Charge at pH 7.41.464
Secondary StructureHelix: 0.163, Turn: 0.245, Sheet: 0.143
Instability Index16.722
Aromaticity0.122

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