Basic Information

IDDRAMP03621
SequenceSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRR
Length47
NameBeta-defensin 125 (Beta-defensin 25, DEFB-25; Defensin, beta 125; Human, mammals, animals)
SourceHomo sapiens (Human)
ActivityAntimicrobial, Antibacterial
PathogenNo MICs found in DRAMP database
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q8N687, A1A502, Q7Z7B9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11854508, 11780052, 12975309

Physicochemical Properties

Residues47
SequenceSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRR
Molecular Weight5730.64
Grand Average of Hydropathy-0.691
Isoelectric Point9.335
Charge at pH 7.45.171
Secondary StructureHelix: 0.277, Turn: 0.191, Sheet: 0.149
Instability Index76.255
Aromaticity0.085

Similar Structure Search

Candidates based on structure

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