Basic Information

IDDRAMP03729
SequenceKWFNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY
Length76
NameOpiscorpine-1 (Arthropods, animals)
SourceOpistophthalmus carinatus (African yellow leg scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
PathogenFungi: Fusarium culmorum IMI180420 (IC50=8.8 µM), Fusarium oxysporum MUCL39789 (IC50=10.04 µM).##Gram-negative bacterium: Escherichia coli JM109 (MIC=12 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q5WR03, Q5WQZ8
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15241551

Physicochemical Properties

Residues76
SequenceKWFNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY
Molecular Weight8428.771
Grand Average of Hydropathy-0.507
Isoelectric Point9.101
Charge at pH 7.45.489
Secondary StructureHelix: 0.224, Turn: 0.224, Sheet: 0.197
Instability Index14.522
Aromaticity0.079

Similar Structure Search

Candidates based on structure

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