Basic Information

IDDRAMP03736
SequenceGKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNFVAEKIGATPS
Length44
NameOpistoporin-2 (OP2; Non-disulfide-bridged peptide 3.6, NDBP-3.6; Arthropods, animals)
SourceOpistophthalmus carinatus (African yellow leg scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Swiss_Prot Entry P83314]strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity.
Hemolytic Activity[Swiss_Prot Entry P83314]Weak hemolytic activity against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83314
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12354111

Physicochemical Properties

Residues44
SequenceGKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNFVAEKIGATPS
Molecular Weight4870.562
Grand Average of Hydropathy-0.541
Isoelectric Point9.779
Charge at pH 7.43.541
Secondary StructureHelix: 0.273, Turn: 0.250, Sheet: 0.273
Instability Index15.961
Aromaticity0.091

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