Basic Information
| ID | DRAMP03748 |
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| Sequence | FRFGSFLKKVWKSKLAKKLRSKGKQLLKDYANKVLNGPEEEAAAPAE |
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| Length | 47 |
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| Name | Bradykinin-potentiating peptide BmK3 (Bpp BmK3; NDBP-3.3; Arthropods, animals) |
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| Source | Mesobuthus martensii (Manchurian scorpion) (Buthus martensii) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.22115565]Gram-negative bacteria: Escherichia coli DH 5-α (MIC=2.3 µM), Haemophilus influenzae ATCC 31517 (MIC=3.2 µM), Klebsiella pneumoniae ATCC 13882 (MIC=2.8 µM), Salmonella enterica ATCC 8090 (MIC=2.3 µM), Pseudomonas aeruginosa ATCC 9229 (MIC=4.7 µM), Serratia marcescens ATCC 13880 (MIC=68.2 µM);##Gram-positive bacteria: Bacillus subtilis ATCC 6051 (MIC=24.4 µM), Listeria monocytogenes ATCC 35152 (MIC=5.7 µM), Micrococcus luteus ATCC 9341 (MIC=20.3 µM), Enterococcus faecalis ATCC 14508 (MIC=57.1 µM), Nocardia asteroides ATCC 3308 (MIC>70 µM), Staphylococcus aureus ATCC 14458 (MIC>70 µM);##Fungi: Neurospora crassa FGSC 2489 (IC50=2 µM), Botrytis cinerea ATCC 28387 (IC50=3.1 µM), Fusarium culmorum ATCC 32973 (IC50=0.2 µM). |
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| Hemolytic Activity | [Ref.22115565]3.5% hemolytic activity at 6 μM, 11.2% hemolytic activity at 10 μM, 22.5% hemolytic activity at 30 μM, 33.9% hemolytic activity at 50 μM against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q9Y0X4 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10868911, 22115565 |
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