Basic Information
| ID | DRAMP03734 |
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| Sequence | FKLGSFLKKAWKSKLAKKLRAKGKEMLKDYAKGLLEGGSEEVPGQ |
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| Length | 45 |
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| Name | Parabutoporin (PP; Non-disulfide-bridged peptide 3.2, NDBP-3.2; Arthropods, animals) |
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| Source | Parabuthus schlechteri (Scorpion) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.12354111]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.1 µM), Escherichia coli DH5a (MIC=3.1 µM), Pseudomonas aeruginosa ATCC 257853 (MIC=6.3 µM), Klebsiella pneumoniae ATCC 13833 (MIC=1.6 µM), Salmonella choleraesuis ATCC 13311 (MIC=3.1 µM), Haemophilus influenzae ATCC 19418 (MIC=3.1 µM);##Gram-positive bacteria: Bacillus subtilis ATCC 6051 (MIC=6.3 µM), Listeria monocytogenes NCTC 11994 (MIC=6.3 µM), Micrococcus luteus ATCC 9341 (MIC=25 µM);##Fungi: Neurospora crassa (MIC=2.5 µM), Botrytis cinerea (MIC=3.5 µM), Fusarium culmorum (MIC=0.3 µM), Saccharomyces cerevisiae (MIC=2 µM). |
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| Hemolytic Activity | [Ref.12354111]50% hemolysis is induced by about 38 µM against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P83312 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 12354111, 12457879, 14575699, 15245865 |
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