Basic Information

IDDRAMP03754
SequenceGFWGKLWEGVKSAI
Length14
NameAmphipathic peptide CT2 (StCT2; Non-disulfide-bridged peptide 5, NDBP-5; Arthropods, animals)
SourceScorpiops tibetanus (Scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus AB94004 (MIC=6.25 µg/ml), Bacillus thuringensis AB92037 (MIC=50 µg/ml), Bacillus subtilis AB91021 (MIC=25 µg/ml), Micrococcus luteus AB93113 (MIC=25 µg/ml), PRSA P1383 (MIC=12.5 µg/ml), PRSE P1389 (MIC=12.5 µg/ml), MRCNS P1369 (MIC=6.25 µg/ml), MRSA P1374 (MIC=6.25 µg/ml), MRSA P1386 (MIC=12.5 µg/ml), MRSA P1381 (MIC=25 µg/ml), MSSE P1111 (MIC=6.25 µg/ml);##Gram-negative bacteria: Escherichia coli AB94012 (MIC=50 µg/ml), Pseudomonas aeruginosa AB93066 (MIC>100 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0DJO4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22542475

Physicochemical Properties

Residues14
SequenceGFWGKLWEGVKSAI
Molecular Weight1577.823
Grand Average of Hydropathy0.143
Isoelectric Point8.591
Charge at pH 7.40.554
Secondary StructureHelix: 0.429, Turn: 0.286, Sheet: 0.214
Instability Index4.607
Aromaticity0.214

Similar Structure Search

Candidates based on structure

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