Basic Information

IDDRAMP03815
SequenceGILDTLKQFAKGVGKWLVKGAAQ
Length23
NameD16W-N23 (single amino acid substitution)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Micrococcus luteus (MIC=2.5 µg/ml), Bacillus subtilis (MIC=25 µg/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=25 µg/ml), Shigella dysentariae (MIC=50 µg/ml), Pseudomonas aeruginosa (MIC=125 µg/ml), Eshchericia coli (MIC=25 µg/ml), Salmonella typhimurium (MIC=125 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12199716

Physicochemical Properties

Residues23
SequenceGILDTLKQFAKGVGKWLVKGAAQ
Molecular Weight2428.869
Grand Average of Hydropathy0.139
Isoelectric Point10.001
Charge at pH 7.42.548
Secondary StructureHelix: 0.348, Turn: 0.174, Sheet: 0.261
Instability Index-3.322
Aromaticity0.087

Similar Structure Search

Candidates based on structure

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