Basic Information

IDDRAMP04173
SequenceWLLKW
Length5
NameL2KW2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC>80 µg/ml), S. aureus (MIC>80 µg/ml), S. epidermis (MIC>80 µg/ml), M. luteus (MIC>80 µg/ml), S. aureus (MRSA) (MIC>80 µg/ml).##Gram-negative bacteria: E. coli (MIC>80 µg/ml), S. dysentariae (MIC>80 µg/ml), S. typhimorium (MIC>80 µg/ml), K. pneumoniae (MIC>80 µg/ml), P. aeruginosa (MIC>80 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues5
SequenceWLLKW
Molecular Weight744.923
Grand Average of Hydropathy0.38
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.800, Turn: 0.000, Sheet: 0.400
Instability Index15.7
Aromaticity0.4

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.