Basic Information

IDDRAMP04175
SequenceKWLLKWL
Length7
NameL3K2W2 (LlKmW2 model peptides)
SourceSynthetic construct (De novo design)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: B. subtilis (MIC=20 µg/ml), S. aureus (MIC=20 µg/ml), S. epidermis (MIC=80 µg/ml), M. luteus (MIC=80 µg/ml), S. aureus (MRSA) (MIC>80 µg/ml).##Gram-negative bacteria: E. coli (MIC=40 µg/ml), S. dysentariae (MIC>80 µg/ml), S. typhimorium (MIC>80 µg/ml), K. pneumoniae (MIC=80 µg/ml), P. aeruginosa (MIC=80 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20736034

Physicochemical Properties

Residues7
SequenceKWLLKWL
Molecular Weight986.252
Grand Average of Hydropathy0.257
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.714, Turn: 0.000, Sheet: 0.429
Instability Index31.7
Aromaticity0.286

Similar Structure Search

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