Basic Information

IDDRAMP18367
SequenceGFGSKPLDSFGLNFF
Length15
NameChaxapeptin (a class 2 lasso peptide; class 1 microcin, bacteriocins)
SourceStreptomyces leeuwenhoekii Strain C58
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-cancer
PathogenGram-positive bacteria: S. aureus and B. subtilis (MIC 30-35 ug/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26402731

Physicochemical Properties

Residues15
SequenceGFGSKPLDSFGLNFF
Molecular Weight1632.812
Grand Average of Hydropathy0.233
Isoelectric Point5.836
Charge at pH 7.4-0.445
Secondary StructureHelix: 0.400, Turn: 0.467, Sheet: 0.133
Instability Index7.127
Aromaticity0.267

Similar Structure Search

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