Basic Information

IDDRAMP21466
SequenceAAGKGLVSNLLEK
Length13
NameP2-Ll-1298 (De Novo Synthesis)
Source Leptodactylus latrans (Anura: Leptodactylidae)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.30423858] Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=49μM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=24.6μM)
Hemolytic Activity[Ref.30423858] 100% hemolysis MHC=320μM against human blood cells
Cytotoxicity[Ref.30423858] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID30423858

Physicochemical Properties

Residues13
SequenceAAGKGLVSNLLEK
Molecular Weight1299.516
Grand Average of Hydropathy0.215
Isoelectric Point8.635
Charge at pH 7.40.604
Secondary StructureHelix: 0.308, Turn: 0.308, Sheet: 0.462
Instability Index-3.831
Aromaticity0

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