Basic Information

IDDRAMP18489
SequenceRKCNFLCKLKEKLRTVITSHIDKVLRPQG
Length29
NameCathelicidin-PY (Frog, amphibians, animals; BBL)
SourcePaa yunnanensis(Chinese Yunnan frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-inflammatory
Pathogen[Ref.23594231]Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=2.74 µM).
Hemolytic Activity[Ref.23594231]2.5% hemolytic activity at 12.5 μg/mL, 3.5 hemolytic activity at 25 μg/mL, 5.5% hemolytic activity at 50 μg/mL against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB 2LR7
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23594231

Physicochemical Properties

Residues29
SequenceRKCNFLCKLKEKLRTVITSHIDKVLRPQG
Molecular Weight3425.125
Grand Average of Hydropathy-0.483
Isoelectric Point10.203
Charge at pH 7.45.534
Secondary StructureHelix: 0.310, Turn: 0.138, Sheet: 0.172
Instability Index31.552
Aromaticity0.034

Similar Structure Search

Candidates based on structure

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