Basic Information
| ID | DRAMP18622 |
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| Sequence | FLPIVAKLLSGLLGRKKRRQRRR |
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| Length | 23 |
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| Name | Temporin-PEb (Temporin-PE peptide derivative) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anitifungal |
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| Pathogen | [Ref.29191658]Gram-positive bacteria: Staphylococcus aureus (MIC=1.0 μM), Methicillin-resistant Staphylococcus aureus (MIC=2.0 μM), Enterococcus faecalis (MIC=2.0 μM);##Gram-negative bacteria: Escherichia coli (MIC=2.0 μM);##Fungus: Candida albicans (MIC=1.0 μM).##Cancer cell lines: NCI-H157 (IC50=3.464 μM), U251MG (IC50=3.087 μM), PC-3 (IC50=3.051 μM), MDA-MB-435s (IC50=3.483 μM), HMEC-1 (IC50=9.976 μM). |
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| Hemolytic Activity | [Ref.29191658]HC50=44.64 μM against horse red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 29191658 |
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