Basic Information
| ID | DRAMP20784 |
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| Sequence | FLKGCWTKWYSLKPKCPF |
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| Length | 18 |
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| Name | Megin 1 |
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| Source | Amphibian skin |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.27114317] Gram-negative bacteria: Escherichia coli (ATCC 25922)(MIC=25μg/mL);B. dysenteriae(MIC=3μg/mL);##Gram-positive bacteria:Staphylococcus aureus (ATCC 2592)(MIC=6.25μg/mL);Bacillus subtilis (ATCC 6633)(MIC=3μg/mL) ;##Fungi:C.albicans (ATCC 2002)(MIC=50μg/mL) |
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| Hemolytic Activity | [Ref.27114317] Human red blood cells: 2.3% hemolysis at 25μg/ml; 5.6% hemolysis at 50μg/ml; 18.7% hemolysis at 100μg/ml; 29.5% hemolysis at 200μg/ml. Rabbit red blood cells :3.1% hemolysis at 25μg/ml; 7.3% hemolysis at 50μg/ml; 20.5% hemolysis at 100μg/ml; 32.9% hemolysis at 200μg/ml |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 27114317 |
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