Basic Information
| ID | DRAMP20821 |
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| Sequence | FRIRVRVFKRIVQRIKDFLR |
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| Length | 20 |
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| Name | FV-LL (FV7 and LL(LL-37,(17-29)) hybrid peptide) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.28178190] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=2 μM), Streptococcus Faecalis ATCC 29212 (MIC=4 μM), Bacillus subtilis CMCC 63501 (MIC=4 μM), Staphylococcus epidermidis ATCC 12228 (MIC=1 μM);##Gram-negative bacteria:Escherichia coli ATCC 25922 (MIC=1 μM), Escherichia coli UB 1005 (MIC=4 μM), Pseudomonas aeruginosa ATCC 27853 (MIC=4 μM), Pseudomonas aeruginosa PAO1 (MIC=2 μM), Salmonella typhimurium ATCC 14028 (MIC=2 μM), Salmonella typhimurium ATCC 7731 (MIC=2 μM). |
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| Hemolytic Activity | [Ref.28178190] 2% hemolysis at 128 μM against human red cells |
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| Cytotoxicity | [Ref.28178190] No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 28178190 |
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