| ID | DRAMP04016 |
|---|---|
| Sequence | LLGDFFRKAKEKIGKEFKRIVQR |
| Length | 23 |
| Name | LL-23A9 (LL-23 variants) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-negagtive bacteria: Escherichia coli DC2 (MIC=9 µM), Escherichia coli K12 (MIC=80 µM);##Gram-positive bacteria: Staphylococcus aureus mprF (presence of carbonate) (MIC=0.35-0.7 µM), S. aureus mprF (absence of carbonate) (MIC=6 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22185690 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | LLGDFFRKAKEKIGKEFKRIVQR |
| Molecular Weight | 2807.342 |
| Grand Average of Hydropathy | -0.73 |
| Isoelectric Point | 10.549 |
| Charge at pH 7.4 | 4.548 |
| Secondary Structure | Helix: 0.348, Turn: 0.087, Sheet: 0.217 |
| Instability Index | 2.852 |
| Aromaticity | 0.13 |