| ID | DRAMP04017 |
|---|---|
| Sequence | LLGDFFRKVKEKIGKEFKRIVQR |
| Length | 23 |
| Name | LL-23V9 (LL-23 variants) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: Escherichia coli DC2 (MIC=2 µM), Escherichia coli K12 (MIC=40 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 µM), S. aureus mprF (presence of carbonate) (MIC=0.35-0.7 µM), S. aureus mprF (absence of carbonate) (MIC=6 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22185690 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | LLGDFFRKVKEKIGKEFKRIVQR |
| Molecular Weight | 2835.395 |
| Grand Average of Hydropathy | -0.626 |
| Isoelectric Point | 10.549 |
| Charge at pH 7.4 | 4.548 |
| Secondary Structure | Helix: 0.391, Turn: 0.087, Sheet: 0.174 |
| Instability Index | -2.091 |
| Aromaticity | 0.13 |