Basic Information

IDDRAMP20994
SequenceGLLKFIKKLL
Length10
Nameanoplin analog 4
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=15 μg/ml), Bacillus subtilis DELTA (MIC=30 μg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=300 μg/ml), Zymomonas mobilis 10988 (MIC=7 μg/ml);##Fungi : Candida parapsilosis (MIC=40 μg/ml)
Hemolytic Activity[Ref.27862650]0% hemolysis at 55μg/ml , 7% hemolysis at 100μg/ml , 17% hemolysis at 200μg/ml , 24% hemolysis at 300 μg/ml , 33% hemolysis at 400μg/ml , 35% hemolysis at 500 μg/ml against human red blood cells
Cytotoxicity[Ref.27862650] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID27862650

Physicochemical Properties

Residues10
SequenceGLLKFIKKLL
Molecular Weight1172.545
Grand Average of Hydropathy1.04
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.600, Turn: 0.100, Sheet: 0.400
Instability Index-16.47
Aromaticity0.1

Similar Structure Search

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