Basic Information
| ID | DRAMP21037 |
|---|
| Sequence | RWKIFKKIkKFLHSAKKF |
|---|
| Length | 18 |
|---|
| Name | PapMA-k (Derived from Papiliocin and Magainin 2) |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.26053120] Gram-positive bacteria : Bacillus subtilis(MIC=4.0 μM), Enterococcus faecalis(MIC=16 μM), Staphylococcus aureus(MIC=4.0 μM), ;##Gram-negative bacteria : Escherichia coli(MIC=2.0 μM), Pseudomonas aeruginosa(MIC=4.0 μM), Salmonella typhimurium(MIC=2.0 μM) |
|---|
| Hemolytic Activity | [Ref.26053120] MHC=200 μM against human red blood cells |
|---|
| Cytotoxicity | [Ref.26053120] IC50 = 42 μM against mouse macrophage-derived RAW264.7 cells. ##IC50 = 39 μM for NIH3T3 fibroblasts. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 26053120 |
|---|
