Basic Information

IDDRAMP21165
SequenceGIMSSLMKKLKKIIKK
Length16
NameHYL-11 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=54 μM), Staphylococcus epidermidis(MIC=1.7 μM);##Gram-negative bacteria : Escherichia coli(MIC=22 μM), Pseudomonas aeruginosa 5482(MIC=7.1 μM);##Fungi : Candida albicans(MIC=6.3 μM)
Hemolytic Activity[Ref.26998557] LC50>400 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGIMSSLMKKLKKIIKK
Molecular Weight1846.435
Grand Average of Hydropathy-0.031
Isoelectric Point10.699
Charge at pH 7.45.542
Secondary StructureHelix: 0.312, Turn: 0.188, Sheet: 0.250
Instability Index22.344
Aromaticity0

Similar Structure Search

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