Basic Information

IDDRAMP21218
SequenceIRVKIRVKIRVK
Length12
NameIK12-all L (De novo synthesis)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=2.0 mg/L), Staphylococcus aureus(MIC=31.3 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=15.6 mg/L), Pseudomonas aeruginosa(MIC=62.5 mg/L);##Fungi : Candida albicans(MIC=125 mg/L)
Hemolytic Activity[Ref.24211081] HC10>125 mg/L against rabbit red blood cells
Cytotoxicity[Ref.24211081] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID24211081

Physicochemical Properties

Residues12
SequenceIRVKIRVKIRVK
Molecular Weight1507.955
Grand Average of Hydropathy0.075
Isoelectric Point12
Charge at pH 7.45.55
Secondary StructureHelix: 0.500, Turn: 0.000, Sheet: 0.000
Instability Index-12.183
Aromaticity0

Similar Structure Search

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