Basic Information
| ID | DRAMP21618 |
|---|
| Sequence | PLILLRLLRGQF |
|---|
| Length | 12 |
|---|
| Name | WWSP |
|---|
| Source | Synthetic construct |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.28921993] Gram-positive bacteria: Staphylococcus aureus (MIC = 16 μg/mL), Enterococcus faecalis (MIC = 64 μg/mL);##Gram-negative bacteria: Escherichia coli (MIC = 256 μg/mL), Pseudomonas aeruginosa (MIC > 256 μg/mL) |
|---|
| Hemolytic Activity | [Ref.28921993] 3.9%, 2.6%, 3.6%, 4.3%, 4.0%, 4.6%, 3.3% and 2.9% hemolysis against human red blood cells at 5, 7.5, 10, 15, 20, 25, 30 and 40 μg/ml. |
|---|
| Cytotoxicity | [Ref.28921993] The toxicity of WWSP toward HEK293 and HeLa cells is much less than nonaarginine (R9) by use of flow cytometry and the peptide doesn't show any cytotoxicity at 2 μM. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 28921993 |
|---|
