| ID | DRAMP29045 |
|---|---|
| Sequence | SQRKLAAKLTSKGGGRLLRPLLQLLKQKLR |
| Length | 30 |
| Name | PA2-GNU7 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.31704464] Gram-positive bacteria: S. aureus (MIC = 2 μM);##Gram-negative bacteria: P. aeruginosa (MIC = 2 μM), E. coli (MIC = 1 μM), S. typhimurium (MIC = 2 μM); ##Fungi: C.albicans (MIC = 8 μM) |
| Hemolytic Activity | [Ref.31678742]PA2-GNU7 was not toxic to human RBCs at the tested concentrations (0 - 65 μM).The haemolysis was less than 2.5 % up to the concentration of 65 μM. |
| Cytotoxicity | Not found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 31678742 |
Physicochemical Properties
| Residues | 30 |
|---|---|
| Sequence | SQRKLAAKLTSKGGGRLLRPLLQLLKQKLR |
| Molecular Weight | 3372.109 |
| Grand Average of Hydropathy | -0.51 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 8.241 |
| Secondary Structure | Helix: 0.300, Turn: 0.200, Sheet: 0.367 |
| Instability Index | 48.17 |
| Aromaticity | 0 |