| ID | DRAMP29057 |
|---|---|
| Sequence | RIVQRIKKWLLKWKKLGY |
| Length | 18 |
| Name | P5 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.31778756] Gram-negative bacteria: P. aeruginosa (MIC = 64 μg/mL, MBC = 128 μg/mL); ##Gram-positive bacteria: S. aureus (MIC = 16 µg/mL, MBC = 64 μg/mL) |
| Hemolytic Activity | [Ref.31778756]P5 displayed less than 10% hemolysis in all the range tested (0-1024 μg/mL) |
| Cytotoxicity | Not found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 31778756 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | RIVQRIKKWLLKWKKLGY |
| Molecular Weight | 2356.941 |
| Grand Average of Hydropathy | -0.606 |
| Isoelectric Point | 11.264 |
| Charge at pH 7.4 | 6.542 |
| Secondary Structure | Helix: 0.500, Turn: 0.056, Sheet: 0.167 |
| Instability Index | -7.283 |
| Aromaticity | 0.167 |