Basic Information

IDDRAMP29121
SequenceGNLKALAAVAKKIL
Length14
NameMastoparan-C [L1G, L7A]
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC>128 µM); Bacillus subtilis ATCC 23857(MIC=8 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=64 µM); Pseudomonas aeruginosa ATCC 9027(MIC=64 µM); Klebsiella pneumoniae ATCC 700603(MIC=128 µM).
Hemolytic Activity[Ref.33285267]0% hemolysis against mouse erythrocytes at 256 µM.
Cytotoxicity[Ref.33285267]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01516
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33285267

Physicochemical Properties

Residues14
SequenceGNLKALAAVAKKIL
Molecular Weight1409.759
Grand Average of Hydropathy0.836
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.357, Turn: 0.143, Sheet: 0.500
Instability Index4.85
Aromaticity0

Similar Structure Search

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