Basic Information

IDDRAMP29126
SequenceLNLKALLAVAKK
Length12
NameMastoparan-C (1-12)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-
Pathogen[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC>128 µM); Bacillus subtilis ATCC 23857(MIC>128 µM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC>128 µM); Pseudomonas aeruginosa ATCC 9027(MIC>128 µM); Klebsiella pneumoniae ATCC 700603(MIC>128 µM).
Hemolytic Activity[Ref.33285267]0% hemolysis against mouse erythrocytes at 256 µM.
Cytotoxicity[Ref.33285267]No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01516
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID33285267

Physicochemical Properties

Residues12
SequenceLNLKALLAVAKK
Molecular Weight1281.63
Grand Average of Hydropathy0.8
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.417, Turn: 0.083, Sheet: 0.583
Instability Index2.092
Aromaticity0

Similar Structure Search

Candidates based on structure

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