Basic Information

IDdbAMP25146
SequenceGLPALISWSKRKRQQ
Length15
NameMelittin (12-26)[I9S]&&Mel(12-26,S9)
Source
ActivityAntibacterial
PathogenStaphylococcus aureus ATCC 25923 (MIC=20.6µg/ml)&&RBCs Source of Human (HC10 =6140µg/ml)&&Escherichia coli ATCC 25922 (MIC=100µM)&&Bacillus subtilis ATCC 23857 (MIC=32µM)
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14596922

Physicochemical Properties

Residues15
SequenceGLPALISWSKRKRQQ
Molecular Weight1768.071
Grand Average of Hydropathy-0.96
Isoelectric Point12
Charge at pH 7.43.552
Secondary StructureHelix: 0.267, Turn: 0.267, Sheet: 0.200
Instability Index104.16
Aromaticity0.067

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