Basic Information

IDDRAMP00074
SequenceATRSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGMGH
Length44
NameEnterocin P (Pediocin-like peptide; Bacteriocin)
SourceEnterococcus faecium P13 (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.9361419]Gram-positive bacteria: Pediococcus acidilactici (MIC=69 ng/ml), Pediococcus pentosaceus FBB61 (MIC=136 ng/ml), P. pntosaceus FBB63 (MIC=18 ng/ml), Lactococcus lactis BB24 (MIC=22 ng/ml), Enterococcus faecium (MIC=2 ng/ml), E. faecalis (MIC=238 ng/ml), Staphylococcus carnosus (MIC=139 ng/ml), Bacillus cereus (MIC=286 ng/ml), Clostridium sporogenes (MIC=4 ng/ml), Clostridium tyrobutyricum 3, 5CT (MIC=559 ng/ml), C. tyrobutyricum 1754 (MIC=412 ng/ml), Propionibacteruim sp P4 (MIC=37 ng/ml), Propionibacteruim sp P6 (MIC=26 ng/ml), Clostridium tyrobutyricum (MIC=4 ng/ml), Clostridium botulinum (MIC=259 ng/ml), Listeria monocytogenes 7973 (MIC=35 ng/ml), L. monocytogenes LI5sv1/2 (MIC=33 ng/ml), L. monocytogenes 5105 (MIC=18 ng/ml), L. monocytogenes L11sv4 (MIC=39 ng/ml), L. monocytogenes Scott A (MIC=125 ng/ml), Listeria innocua (MIC=395 ng/ml), Streptococcus aureus 137 (MIC=190 ng/ml), S. aureus 196E (MIC=407 ng/ml), S. aureus 349 (MIC=221 ng/ml), S. aureus 361 (MIC=294 ng/ml), S. aureus 472 (MIC=269 ng/ml), Lactobacillus curvatus (MIC=17 ng/ml), L. fermentum (MIC=1 ng/ml), L. sake (MIC=144 ng/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot O30434, Q0GFE0
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9361419, 17103378

Physicochemical Properties

Residues44
SequenceATRSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGMGH
Molecular Weight4630.12
Grand Average of Hydropathy-0.15
Isoelectric Point8.07
Charge at pH 7.40.588
Secondary StructureHelix: 0.273, Turn: 0.386, Sheet: 0.205
Instability Index13.311
Aromaticity0.114

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