Basic Information

IDDRAMP01244
SequenceFFPIGVFCKIFKTC
Length14
NameJaponicin-1 (Frogs, amphibians, animals)
SourceRana japonica (Japanese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=30 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC>100 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys8 and Cys14)
Linear/Cyclic/BranchedCyclic
Uniprot P83305
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11835990

Physicochemical Properties

Residues14
SequenceFFPIGVFCKIFKTC
Molecular Weight1650.058
Grand Average of Hydropathy1.35
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.500, Turn: 0.143, Sheet: 0.000
Instability Index6.243
Aromaticity0.286

Similar Structure Search

Candidates based on structure

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