Basic Information

IDDRAMP04050
SequenceRRRLCPIVIRVCRR
Length14
NameBacP3R-V (cyclic derivative of bactenecin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli K-12 (MIC=2 µg/ml), Pseudomonas aeruginosa K799 (MIC=8 µg/ml), Salmonella typhimurium 14028s (MIC=8 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC>64 µg/ml), Staphylococcus epidermidis C621 (MIC=16 µg/ml), Enterococcus faecalis ATCC 29212 (MIC>64 µg/ml), Listeria monocytogenes (MIC=1 µg/ml), Corynebacterium xerosis (MIC=4 µg/ml), Streptococcus pyogenes ATCC 19615 (MIC=4 µg/ml), S. mitis (MIC=1 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC>64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10223951

Physicochemical Properties

Residues14
SequenceRRRLCPIVIRVCRR
Molecular Weight1796.265
Grand Average of Hydropathy-0.171
Isoelectric Point12
Charge at pH 7.45.508
Secondary StructureHelix: 0.357, Turn: 0.071, Sheet: 0.071
Instability Index139.721
Aromaticity0

Similar Structure Search

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