Basic Information

IDDRAMP01955
SequenceGAIKDALKGAAKTVAVELLKKAQCKLEKTC
Length30
NameBrevinin-2PTa (Frogs, amphibians, animals)
SourceRana picturata (Malaysian fire frog) (Hylarana picturata)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=18 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=18 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys24 and Cys30)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8T3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues30
SequenceGAIKDALKGAAKTVAVELLKKAQCKLEKTC
Molecular Weight3129.78
Grand Average of Hydropathy0.013
Isoelectric Point9.449
Charge at pH 7.43.494
Secondary StructureHelix: 0.233, Turn: 0.067, Sheet: 0.400
Instability Index-12.657
Aromaticity0

Similar Structure Search

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