Basic Information
| ID | DRAMP02036 |
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| Sequence | GAFGNFLKGVAKKAGLKILSIAQCKLSGTC |
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| Length | 30 |
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| Name | Brevinin-2-RN1 (Frogs, amphibians, animals) |
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| Source | Rana nigrovittata |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=3.10 µg/ml), Staphylococcus aureus ATCC43300 (MIC=3.10 µg/ml), Bacillus subtilis (MIC=12.5 µg/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=25 µg/ml), Pseudomonas aeruginosa PA01 (MIC=12.5 µg/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25 µg/ml).##Yeast: Candida albicans ATCC2002 (MIC=6.25 µg/ml). |
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| Hemolytic Activity | [Ref.21171145] It has 17% hemolysis at 100 µg/ml against rabbit red blood cell |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys24 and Cys30) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21171145 |
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