Basic Information

IDDRAMP02315
SequenceFFGWLIKGAIHAGKAIHGLIHRRRH
Length25
NameChrysophsin-1 (fish, chordates, animals)
SourceChrysophrys major (Red sea bream)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.12581207]Gram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=0.25 µM), Lactococcus garvieae ATCC 49156 (MIC=10 µM), S.iniae F-8502 (MIC=2.5 µM);##Gram-negative bacteria: Escherichia coli WT-2 (MIC=0.25 µM), Vibrio anguillarum ATCC 19264 (MIC=2.5 µM), Vibriopenaeicida KHA (MIC=10 µM), V. harveyi ATCC 14126 (MIC=2.5 µM), V. vulnificus ATCC 33148 (MIC=5 µM), Aeromonas salmonicida NCMB 1102 (MIC=10 µM), Pseudomonas putida ATCC 12633 (MIC=40 µM).
Hemolytic Activity[Ref.12581207]10% hemolytic activity at 0.25 μM, 80% hemolytic activity at 1 μM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83545
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12581207

Physicochemical Properties

Residues25
SequenceFFGWLIKGAIHAGKAIHGLIHRRRH
Molecular Weight2892.416
Grand Average of Hydropathy0
Isoelectric Point12
Charge at pH 7.44.699
Secondary StructureHelix: 0.360, Turn: 0.160, Sheet: 0.200
Instability Index70.076
Aromaticity0.12

Similar Structure Search

Candidates based on structure

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