Basic Information

IDDRAMP02316
SequenceFFGWLIRGAIHAGKAIHGLIHRRRH
Length25
NameChrysophsin-2 (fish, chordates, animals)
SourceChrysophrys major (Red sea bream)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.12581207]Gram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=0.25 µM), Lactococcus garvieae ATCC 49156 (MIC=5 µM), S.iniae F-8502 (MIC=1.5 µM);##Gram-negative bacteria: Escherichia coli WT-2 (MIC=0.25 µM), Vibrio anguillarum ATCC 19264 (MIC=1.25 µM), Vibriopenaeicida KHA (MIC=5 µM), V. harveyi ATCC 14126 (MIC=5 µM), V. vulnificus ATCC 33148 (MIC=2.5 µM).
Hemolytic Activity[Ref.12581207]10% hemolytic activity at 0.25 μM, 70% hemolytic activity at 1 μM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83546
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12581207

Physicochemical Properties

Residues25
SequenceFFGWLIRGAIHAGKAIHGLIHRRRH
Molecular Weight2920.43
Grand Average of Hydropathy-0.024
Isoelectric Point12
Charge at pH 7.44.701
Secondary StructureHelix: 0.360, Turn: 0.160, Sheet: 0.200
Instability Index73.472
Aromaticity0.12

Similar Structure Search

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