Basic Information

IDDRAMP02349
SequenceGRRKRKWLRRIGKGVKIIGGAALDHL
Length26
NameNRC-3 (fish, chordates, animals)
SourcePseudopleuronectes americanus (Winter flounder 1a-1)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=2 µg/ml), Aeromonas salmonicida 97-4 (MIC=4 µg/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=2 µg/ml), Salmonella enterica serovar Typhimurium 14028s (MIC=8 µg/ml), Pseudomonas aeruginosa K799 (MIC=2 µg/ml), Pseudomonas aeruginosa Z61 (MIC=1 µg/ml), Escherichia coli CGSC 4908 (MIC=2 µg/ml), Escherichia coli UB1005 (MIC=8 µg/ml), Escherichia coli DC2 (MIC=2 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=8 µg/ml), Staphylococcus aureus (MRSA) C623 (MIC=8 µg/ml).##Yeast: Candida albicans C627 (MIC=4 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12878506

Physicochemical Properties

Residues26
SequenceGRRKRKWLRRIGKGVKIIGGAALDHL
Molecular Weight2955.558
Grand Average of Hydropathy-0.577
Isoelectric Point12
Charge at pH 7.47.584
Secondary StructureHelix: 0.308, Turn: 0.192, Sheet: 0.192
Instability Index68.946
Aromaticity0.038

Similar Structure Search

Candidates based on structure

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