Basic Information

IDDRAMP02367
SequenceFLGLLFHGVHHVGKWIHGLIHGHH
Length24
NamePleurocidin-like peptide Hb26 (NRC-19; fish, chordates, animals; Predicted)
SourceHippoglossus hippoglossus (Halibut Hb26)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=64 µg/ml), A. salmonicida 97-4 (MIC>64 µg/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 µg/ml), S. enterica serovar Typhimurium 14028s (MIC=64 µg/ml), Pseudomonas aeruginosa K799 (MIC=32 µg/ml), Pseudomonas aeruginosa Z61 (MIC=8 µg/ml), Escherichia coli CGSC 4908 (MIC=32 µg/ml), E. coli UB1005 (MIC=16 µg/ml), E. coli DC2 (MIC=32 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=8 µg/ml), Staphylococcus aureus (MRSA) C623 (MIC=8 µg/ml).##Yeast: Candida albicans C627 (MIC=64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q7SZG6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12878506

Physicochemical Properties

Residues24
SequenceFLGLLFHGVHHVGKWIHGLIHGHH
Molecular Weight2749.184
Grand Average of Hydropathy0.375
Isoelectric Point8.796
Charge at pH 7.40.811
Secondary StructureHelix: 0.458, Turn: 0.208, Sheet: 0.167
Instability Index-0.171
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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