Basic Information

IDDRAMP02742
SequenceQKKCPGRCTLKCGKHERPTLPYNCGKYICCVPVKVK
Length36
NameDefensin-like turtle egg white protein TEWP (TEWP; Reptiles, animals)
SourceCaretta caretta (Loggerhead sea turtle)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral
PathogenGram-negative bacteria: Escherichia coli (IC50=3.3 µM), Salmonella typhimurium (IC50=2.8 µM);##Gram-positive bacterium: Staphylococcus aureus (IC50=5. 1µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0CAP0
PDB 2B5B
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16700051

Physicochemical Properties

Residues36
SequenceQKKCPGRCTLKCGKHERPTLPYNCGKYICCVPVKVK
Molecular Weight4079.97
Grand Average of Hydropathy-0.608
Isoelectric Point9.544
Charge at pH 7.47.426
Secondary StructureHelix: 0.222, Turn: 0.222, Sheet: 0.083
Instability Index31.6
Aromaticity0.056

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