Basic Information

IDDRAMP02878
SequenceNPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
Length38
NameTracheal antimicrobial peptide (TAP; mammals, animals)
SourceBos taurus (Bovine)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli D31 (MIC=12-25 µg/ml), Klebsiella pneumoniae 13883 (MIC=12-25 µg/ml), Pseudomonas aeruginosa 27853 (MIC=25-50 µg/ml).##Gram-positive bacteria: Staphylococcus aureus 25923 (MIC=25-50 µg/ml).##Fungi: Candida ablicans (MIC=6-12 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P25068, O97532
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID2023943, 8506305

Physicochemical Properties

Residues38
SequenceNPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
Molecular Weight4091.022
Grand Average of Hydropathy-0.092
Isoelectric Point10.002
Charge at pH 7.48.398
Secondary StructureHelix: 0.211, Turn: 0.289, Sheet: 0.053
Instability Index32.816
Aromaticity0

Similar Structure Search

Candidates based on structure

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