| ID | DRAMP02872 |
|---|---|
| Sequence | GRFKRFRKKFKKLFKKLS |
| Length | 18 |
| Name | Myeloid antimicrobial peptide BMAP-27 (1-18) (mammals, animals) |
| Source | Bos taurus (Bovine) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 µM), Escherichia coli ML35 (MIC=4 µM), Escherichia coli D21 (MIC=4 µM), Salmonella typhimurium ATCC 14028 (MIC=4 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=1 µM), Serratia marcescens ATCC 8100 (MIC=2 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 µM), Staphylococcus aureus Cowan 1 (MIC=2 µM), Staphylococcus aureus (MRSA) (MIC=4 µM), Staphylococcus epidermidis ATCC 12228 (MIC=1 µM), Bacillus megaterium Bm11 (MIC=2 µM).##Fungi: Candida albicans (MIC=16 µM), Cryptococcus neoformans (MIC=4 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8910461 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | GRFKRFRKKFKKLFKKLS |
| Molecular Weight | 2342.918 |
| Grand Average of Hydropathy | -1.289 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 9.54 |
| Secondary Structure | Helix: 0.333, Turn: 0.111, Sheet: 0.111 |
| Instability Index | -6.928 |
| Aromaticity | 0.222 |
