Basic Information

IDDRAMP02872
SequenceGRFKRFRKKFKKLFKKLS
Length18
NameMyeloid antimicrobial peptide BMAP-27 (1-18) (mammals, animals)
SourceBos taurus (Bovine)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 µM), Escherichia coli ML35 (MIC=4 µM), Escherichia coli D21 (MIC=4 µM), Salmonella typhimurium ATCC 14028 (MIC=4 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=1 µM), Serratia marcescens ATCC 8100 (MIC=2 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 µM), Staphylococcus aureus Cowan 1 (MIC=2 µM), Staphylococcus aureus (MRSA) (MIC=4 µM), Staphylococcus epidermidis ATCC 12228 (MIC=1 µM), Bacillus megaterium Bm11 (MIC=2 µM).##Fungi: Candida albicans (MIC=16 µM), Cryptococcus neoformans (MIC=4 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8910461

Physicochemical Properties

Residues18
SequenceGRFKRFRKKFKKLFKKLS
Molecular Weight2342.918
Grand Average of Hydropathy-1.289
Isoelectric Point12
Charge at pH 7.49.54
Secondary StructureHelix: 0.333, Turn: 0.111, Sheet: 0.111
Instability Index-6.928
Aromaticity0.222

Similar Structure Search

Candidates based on structure

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