Basic Information

IDDRAMP03753
SequenceGFWGSLWEGVKSVV
Length14
NameAmphipathic peptide CT1 (StCT1; Non-disulfide-bridged peptide 5, NDBP-5; Arthropods, animals)
SourceScorpiops tibetanus (Scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus AB94004 (MIC=12.5 µg/ml), Bacillus thuringensis AB92037 (MIC>100 µg/ml), Bacillus subtilis AB91021 (MIC>100 µg/ml), Micrococcus luteus AB93113 (MIC=100 µg/ml), MRSA P1374 (MIC=200 µg/ml), MRSA P1386 (MIC=250 µg/ml);##Gram-negative bacteria: Escherichia coli AB94012 (MIC=100 µg/ml), Pseudomonas aeruginosa AB93066 (MIC=100 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0DJO3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19854232

Physicochemical Properties

Residues14
SequenceGFWGSLWEGVKSVV
Molecular Weight1550.754
Grand Average of Hydropathy0.514
Isoelectric Point6.001
Charge at pH 7.4-0.444
Secondary StructureHelix: 0.500, Turn: 0.357, Sheet: 0.143
Instability Index16.736
Aromaticity0.214

Similar Structure Search

Candidates based on structure

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