Basic Information

IDDRAMP04095
SequenceGFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHMQ
Length35
NameCupiennin-1D (spiders, Arthropods, animals)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.11792701]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=0.31-0.63 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=0.31-0.63 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=0.31-0.63 µM), Enterococcus faecalis ATCC 29212 (MIC=1.25-2.50 µM).
Hemolytic Activity[Swiss_Prot Entry P83622]has hemolytic activity
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83622
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11792701, 10669026

Physicochemical Properties

Residues35
SequenceGFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHMQ
Molecular Weight3795.502
Grand Average of Hydropathy-0.266
Isoelectric Point10.544
Charge at pH 7.47.572
Secondary StructureHelix: 0.257, Turn: 0.143, Sheet: 0.286
Instability Index18.689
Aromaticity0.114

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