Basic Information

IDDRAMP01909
SequenceGFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
Length34
NameBrevinin-2GHa (AMP-1; Frogs, amphibians, animals)
SourceRana guentheri (Gunther's frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Staphylococcus aureus FDA209P (MIC=14.9 µg/ml), Bacillus subtilis ATCC 6633 (MIC>64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P84860
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16979798

Physicochemical Properties

Residues34
SequenceGFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
Molecular Weight3416.969
Grand Average of Hydropathy0.165
Isoelectric Point9.789
Charge at pH 7.44.493
Secondary StructureHelix: 0.235, Turn: 0.265, Sheet: 0.353
Instability Index16.206
Aromaticity0.088

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.