Basic Information

IDDRAMP18493
SequenceFIHHIIGGLISVGKHIHGLIHGH
Length23
NameTP3
SourceOreochromis niloticus (Nile tilapia) (Tilapia nilotica)
ActivityAntibacterial, wound healing, immunomodulatory, Anti-Gram+, Antimicrobial
Pathogen[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=256 μg/ml; MBC=256 μg/ml), Methicillin-resistant Staphylococcus aureus (MIC=256 μg/ml; MBC>256 μg/ml);##Fungi: Candida albicans (MIC=128 μg/ml; MBC=128 μg/ml)
Hemolytic Activity[Ref.29040295] 2% hemolysis at 3.13 μg/ml, 5% hemolysis at 6.25 μg/ml, 10% hemolysis at 12.50 μg/ml, 55% hemolysis at 25.00 μg/ml, 85% hemolysis at 50.00 μg/ml, 100% hemolysis at 100.00 μg/ml against mouse red blood cell
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot L0CMD2
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29040295

Physicochemical Properties

Residues23
SequenceFIHHIIGGLISVGKHIHGLIHGH
Molecular Weight2492.923
Grand Average of Hydropathy0.683
Isoelectric Point8.79
Charge at pH 7.40.775
Secondary StructureHelix: 0.435, Turn: 0.261, Sheet: 0.087
Instability Index52.835
Aromaticity0.043

Similar Structure Search

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