Basic Information

IDDRAMP20792
SequenceGLFVGVLAKVAAHVVPAIAEHF
Length22
NameMaculatin 1.1 (Frog, amphibians, animals)
SourceLitoria genimaculata (Green-eyed tree frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.9620615] Gram positive bacteria: Bacillus cereus (MIC=50 μg/ml), Leuconostoc lactis (MIC=25 μg/ml), Listeria innocua (MIC=100 μg/ml), Micrococcus luteus (MIC=12.5 μg/ml), Staphylococcus aureus (MIC=6-12.5 μg/ml), Staphylococcus epidermidis (MIC=12.5 μg/ml), Streptococcus faecalis (MIC=25 μg/ml), Streptococcus uberis (MIC=3 μg/ml);##Gram-negative bacteria: Escherichia coli (MIC=100 μg/ml), Pasteurella multocida (MIC=100 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.9620615] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82066
PDB 2MMJ resolved by NMR
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9620615

Physicochemical Properties

Residues22
SequenceGLFVGVLAKVAAHVVPAIAEHF
Molecular Weight2245.663
Grand Average of Hydropathy1.432
Isoelectric Point6.921
Charge at pH 7.4-0.371
Secondary StructureHelix: 0.455, Turn: 0.136, Sheet: 0.364
Instability Index7.336
Aromaticity0.091

Similar Structure Search

Candidates based on structure

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