Basic Information

IDDRAMP20938
SequenceRLLRKFFRKLKKSV
Length14
NameCbf-14
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.28522372]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=64 μg/ml), Staphylococcus aureus (MIC=32 μg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=32 μg/ml), Escherichia coli (MIC=32 μg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=16 μg/ml), Pseudomonas aeruginosa (MIC=32 μg/ml);##Yeasts: Candida albicans ATCC 10231 (MIC=64 μg/ml), Candida albicans (MIC=64 μg/ml)
Hemolytic Activity[Ref.28522372]2% hemolysis at 800 μg/ml against mice red blood cells
CytotoxicityThe percentages of possible occurring conformations involved helix, beta, turn and random are also quantified in various solutions
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID28522372

Physicochemical Properties

Residues14
SequenceRLLRKFFRKLKKSV
Molecular Weight1819.29
Grand Average of Hydropathy-0.621
Isoelectric Point12
Charge at pH 7.46.547
Secondary StructureHelix: 0.429, Turn: 0.071, Sheet: 0.214
Instability Index10.914
Aromaticity0.143

Similar Structure Search

Candidates based on structure

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