Basic Information
| ID | DRAMP20946 |
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| Sequence | TRSRWRRFIRGAGRFARRYGWRIA |
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| Length | 24 |
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| Name | ΔPb-CATH4 bivittatus antimicrobial peptides peptide derivative |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial |
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| Pathogen | [Ref.28630199] Gram-negative bacteria: Escherichia coli (ATCC 25922)(MIC=1μg/ml);Pseudomonas aeruginosa (ATCC 27853)(MIC=3μg/ml);S. typhimurium (ATCC 14028)(MIC=0.5μg/ml);##Gram-positive bacteria: Staphylococcus aureus (ATCC 29213)(MIC>128μg/ml);B. cereus (ATCC 10876)(MIC=10μg/ml);##Clinical isolates:Escherichia coli(MIC=4.7μg/ml);K. pneumoniae(MIC=1.18μg/ml) |
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| Hemolytic Activity | [Ref.28630199]Hemolysis 0% at 4μg/ml against human red blood cell;Hemolysis 1.2 ± 0.3% at 8μg/ml against human red blood cell;Hemolysis 3.2 ± 0.4% at 16μg/ml against human red blood cell;Hemolysis 6.5 ± 0.4% at 32μg/ml against human red blood cell;Hemolysis 10.7 ± 0.2% at 64μg/ml against human red blood cell |
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| Cytotoxicity | [Ref.28630199] No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 28630199 |
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