Basic Information

IDDRAMP21457
SequenceGVKELFGKAWGLVKKHLPKACGLLGYVKQ
Length29
NamePLP4 (Insects, animals)
SourceOdontomachus monticola (Trap-jaw ant)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<3.1μM);##Gram-negative bacteria:Escherichia coli (MIC<3.1μM);##Fungi:Saccharomyces cerevisiae (MIC<3.1μM)
Hemolytic Activity[Ref.30658410] 10.5% hemolysis at 50 μM against rat blood cells
Cytotoxicity[Ref.30658410] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot A0A348G5W0
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID30658410

Physicochemical Properties

Residues29
SequenceGVKELFGKAWGLVKKHLPKACGLLGYVKQ
Molecular Weight3168.84
Grand Average of Hydropathy0.038
Isoelectric Point9.904
Charge at pH 7.44.553
Secondary StructureHelix: 0.379, Turn: 0.207, Sheet: 0.276
Instability Index27.19
Aromaticity0.103

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