| ID | DRAMP21627 |
|---|---|
| Sequence | TLKQFAKGVGKWLVK |
| Length | 15 |
| Name | E2EM15W |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.24211019] Gram-positive bacteria: Bacillus subtilis (MIC = 200 μg/mL), Staphylococcus aureus (MIC = 100 μg/mL), Staphylococcus epidermis (MIC > 200 μg/mL);##Gram-negative bacteria: Escherichia coli (MIC = 200 μg/mL), Shigella dysentariae (MIC > 200 μg/mL), Salmonella typhimurium (MIC > 200 μg/mL), Klebsiella pneumonia (MIC > 200 μg/mL), Proteus mirabilis (MIC > 200 μg/mL), Pseudomonas aeuginose (MIC > 200 μg/mL). |
| Hemolytic Activity | [Ref.24211019] No hemolytic activity information found. |
| Cytotoxicity | No cytotoxicity information found in the reference |
| N-terminal Modification | Acetylation |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 24211019 |
Physicochemical Properties
| Residues | 15 |
|---|---|
| Sequence | TLKQFAKGVGKWLVK |
| Molecular Weight | 1703.079 |
| Grand Average of Hydropathy | -0.06 |
| Isoelectric Point | 10.477 |
| Charge at pH 7.4 | 3.198 |
| Secondary Structure | Helix: 0.400, Turn: 0.133, Sheet: 0.200 |
| Instability Index | 3.733 |
| Aromaticity | 0.133 |
