Basic Information

IDDRAMP21627
SequenceTLKQFAKGVGKWLVK
Length15
NameE2EM15W
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.24211019] Gram-positive bacteria: Bacillus subtilis (MIC = 200 μg/mL), Staphylococcus aureus (MIC = 100 μg/mL), Staphylococcus epidermis (MIC > 200 μg/mL);##Gram-negative bacteria: Escherichia coli (MIC = 200 μg/mL), Shigella dysentariae (MIC > 200 μg/mL), Salmonella typhimurium (MIC > 200 μg/mL), Klebsiella pneumonia (MIC > 200 μg/mL), Proteus mirabilis (MIC > 200 μg/mL), Pseudomonas aeuginose (MIC > 200 μg/mL).
Hemolytic Activity[Ref.24211019] No hemolytic activity information found.
CytotoxicityNo cytotoxicity information found in the reference
N-terminal ModificationAcetylation
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID24211019

Physicochemical Properties

Residues15
SequenceTLKQFAKGVGKWLVK
Molecular Weight1703.079
Grand Average of Hydropathy-0.06
Isoelectric Point10.477
Charge at pH 7.43.198
Secondary StructureHelix: 0.400, Turn: 0.133, Sheet: 0.200
Instability Index3.733
Aromaticity0.133

Similar Structure Search

Candidates based on structure

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