Basic Information

IDdbAMP01052
SequenceDHYLCVKNEGICLYSSCPSYTKIEGTCYGGKAKCCK
Length36
NameBeta-defensin 1TB
Source
ActivityAntibacterial
PathogenStaphylococcus aureus ATCC 43300 (MIC=3.0µg/ml)&&Staphylococcus aureus ATCC 25923 (MIC=4.5µg/ml)&&Pseudomonas aeruginosa PAO1 (MIC=12.0µg/ml)&&Pseudomonas aeruginosa ATCC 27853 (MIC=12.0µg/ml)&&Escherichia coli ML-35p (MIC=24.0µg/ml)&&Candida albicans ATC
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot J9QU63
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22939868

Physicochemical Properties

Residues36
SequenceDHYLCVKNEGICLYSSCPSYTKIEGTCYGGKAKCCK
Molecular Weight3966.584
Grand Average of Hydropathy-0.314
Isoelectric Point8.287
Charge at pH 7.41.427
Secondary StructureHelix: 0.250, Turn: 0.250, Sheet: 0.139
Instability Index50.972
Aromaticity0.111

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